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Publications

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  • Magaña AJ, Ngo D, Burgos K, Dominguez Maldonado C, Abdelmaksoud O, Sklenicka J, Tran T, Pasteran F, Jimenez V, Ramirez MS, Tolmasky ME. Inhibiting Amikacin Resistance in Multidrug-Resistant Bacteria with Cadmium and Pyrithione. Curr Microbiol. 2025 Jul 16;82(9):389. doi: 10.1007/s00284-025-04372-1. Review. PubMed PMID: 40668405.

  • Augusto I, Girard Dias W, Schoijet A, Alonso GD, Jimenez V, de Souza W, Miranda K. The adhesion plaque mediates fluid discharge and duplication of the contractile vacuole complex in Trypanosoma cruzi. J Cell Sci. 2025 Jul 3;. doi: 10.1242/jcs.263810. [Epub ahead of print] PubMed PMID: 40605743.

  • Augusto I, Girard-Dias W, Schoijet A, Alonso GD, Portugal RV, de Souza W, Jimenez V, Miranda K. Quantitative assessment of the nanoanatomy of the contractile vacuole complex in Trypanosoma cruzi. Life Sci Alliance. 2024 Oct;7(10). doi: 10.26508/lsa.202402826. Print 2024 Oct. PubMed PMID: 39074903; PubMed Central PMCID: PMC11287019.

  • Sklenicka J, Tran T, Ramirez MS, Donow HM, Magaña AJ, LaVoi T, Mamun Y, Jimenez V, Chapagain P, Santos R, Pinilla C, Giulianotti MA, Tolmasky ME. Structure-Activity Relationship of Pyrrolidine Pentamine Derivatives as Inhibitors of the Aminoglycoside 6'-N-Acetyltransferase Type Ib. Antibiotics (Basel). 2024 Jul 19;13(7). doi: 10.3390/antibiotics13070672. PubMed PMID: 39061354; PubMed Central PMCID: PMC11274322.

  • Ngo D, Magaña AJ, Tran T, Sklenicka J, Phan K, Eykholt B, , Ramirez MS, Tolmasky ME. Inhibition of Enzymatic Acetylation-Mediated Resistance to Plazomicin by Silver Ions. Pharmaceuticals (Basel). 2023 Feb 3;16(2). doi: 10.3390/ph16020236.

  • Jimenez, V; Mesones, S. Down the membrane hole: ion channels in protozoan parasites. PlosPathogens, 2022 Dec 29;18(12):e1011004.  doi: 10.1371/journal.ppat.1011004. eCollection 2022 Dec. PMID: 36580479.

  • Jimenez V, Miranda K, Augusto I. The old and the new about the contractile vacuole of Trypanosoma cruzi. J Eukaryot Microbiol. 2022 Aug 2;:e12939. doi: 10.1111/jeu.12939. Review. PubMed PMID: 35916682.

  • Magallon J, Vu P, Reeves C, Kwan S, Phan K, Oakley-Havens CL, Rocha K, Ramirez MS, Tolmasky ME. Amikacin potentiator activity of zinc complexed to a pyrithione derivative with enhanced solubility. Sci Rep. 2022 Jan 7;12(1):285. doi: 10.1038/s41598-021-04724-4.

  • Dave N, Cetiner U, Arroyo D, Fonbuena J, Tiwari M, Barrera P, Lander N, Anishkin A, Sukharev S, . A novel mechanosensitive channel controls osmoregulation, differentiation, and infectivity in . Elife. 2021 Jul 2;10. doi: 10.7554/eLife.67449.

  • Martinez J, Razo-Gutierrez C, Le C, Courville R, Pimentel C, Liu C, Fung SE, Tuttobene MR, Phan K, Vila AJ, Shahrestani P, , Tolmasky ME, Becka SA, Papp-Wallace KM, Bonomo RA, Soler-Bistue A, Sieira R, Ramirez MS. Cerebrospinal fluid (CSF) augments metabolism and virulence expression factors in . Sci Rep. 2021 Feb 26;11(1):4737. doi: 10.1038/s41598-021-81714-6.

  • Reeves CM, Magallon J, Rocha K, Tran T, Phan K, Vu P, Yi Y, Oakley-Havens CL, Cedano J, , Ramirez MS, Tolmasky ME. Aminoglycoside 6'-N-acetyltransferase Type Ib [AAC(6')-Ib]-Mediated Aminoglycoside Resistance: Phenotypic Conversion to Susceptibility by Silver Ions. Antibiotics (Basel). 2020 Dec 31;10(1). doi: 10.3390/antibiotics10010029.

  • Barrera, P, Skorka, C; Boktor, M; Dave, N and . Novel Calcium-Activated Potassium Channel Controls Membrane Potential and Intracellular pH in . Front. Cell. Infect. Microbiol., 15 January 2020. https://doi.org/10.3389/fcimb.2019.00464

  • Rodman, N; Martinez, J; Fung, S; Nakanouchi, J; Myers, AL; Harris, C; Dang, E; Fernandez, J; Liu, C; Mendoza, A; ; Nikolaidis, N; Brennan, C; Bonomo, RA; Sieira, R and Ramirez, MS. Human pleural fluid elicits pyruvate and phenylalanine metabolism in Acinetobacter baumannii to enhance cytotoxicity and immune evasion. Front. Microbiol., 17 July 2019 | https://doi.org/10.3389/fmicb.2019.01581

  • Magallon, J; Chiem, K; Tran, T; Ramirez, MS; and Tolmasky ME. 2019. Restoration of susceptibility to amikacin by 8-hydroxyquinoline analogs complexed to zinc. PLoS ONE 14(5): e0217602. https://doi.org/10.1371/journal.

  • Tran, T; Chiem, K; Jani, S; Arivett, B; Lin, D; Lad, R; ; Farone, M; Debevec, G; Santos, R; Giulianotti, M; Pinilla, C and Tolmasky, M. 2018. Identification of a Small Molecule Inhibitor of the Aminoglycoside 6'-N-Acetyltransferase Type Ib [AAC(6')-Ib] Using Mixture-Based Combinatorial Libraries. International Journal of Antimicrobial Agents. doi.org/10.1016/j.ijantimicag.2018.01.019.

  • Jimenez V, Docampo R. 2015. TcPho91 is a contractile vacuole phosphate sodium symporter that regulates phosphate and polyphosphate metabolism in Trypanosoma cruzi. Molecular Microbiology. 2015 Sep;97(5):911-25.

  • Niyogi S, , Gerard-Dias W, de Souza W, Miranda K, Docampo R.2015. Rab32 is Essential for Maintaining Functional Acidocalcisomes and for Growth and Infectivity of Journal of Cell Science. Jun 15;128(12):2363-73.

  • Jimenez V, Kemmerling U, Paredes R, Maya JD, Sosa MA and Galanti N. 2014. Natural sesquiterpene lactones induce programmed cell death in Trypanosoma cruzi: a new therapeutic target? Phytomedicine. Sep 25; 21(11):1411-8.

  • Pace D, Liu J, and Moreno SNJ. 2014. Store-operated calcium entry in the Apicomplexan parasite is nifedipine sensitive and results in significant enhancement of invasion-linked traits. J Biol Chem. Jul 11;289(28):19637-47.

  • Jimenez, V. 2014. Dealing with environmental challenges: mechanisms of adaptation in Trypanosoma cruzi. Res Microbiol. Apr 165(3):155-65.

  • Docampo R, , Lander N, Li ZH and Niyogi S. 2013. New insights into the roles of acidocalcisomes and the contractile vacuole complex in osmoregulation in protists. Int Rev Cell Mol Biol. 305:69-113.

  • Jimenez V and Docampo R. 2012. Molecular and electrophysiological characterization of a novel cation channel of Trypanosoma cruzi. PLoS Pathog. Jun;8(6):e1002750.

  • Docampo R, , King-Keller S, Li Z, Moreno SNJ. 2011. The Role of Acidocalcisomes in the Stress Response of . Adv. Parasitol. 307-24.

  • Ulrich PN#, , Park M, Martins V, Atwood J, Moles K, Collins D, Rohloff P; Tarleton R, Moreno SNJ; Orlando R, Docampo R. 2011.Identification of contractile vacuole proteins in . PlosOne. e18013. # Both authors contributed equally.

  • Jimenez V, Henriquez M, Galanti N, Riquelme G. 2011. Electrophysiological characterization of potassium conductive pathways in Trypanosoma cruzi. J Cell Biochem. 112 (4): 1093–1102.

  • Paredes R, Godoy P, Rodríguez B, García MP, Cabezón C, Cabrera G, , Hellman U, Sáenz L, Ferreira A, Galanti N. 2011. Bovine J Cell Biochem. 189-99.

  • de Jesus TC, Tonelli RR, Nardelli SC, da Silva Augusto L, Motta MC, Girard-Dias W, Miranda K, Ulrich P, , Barquilla A, Navarro M, Docampo R, Schenkman S. 2010. Target of rapamycin (TOR)-like 1 kinase is involved in the control of polyphosphate levels and acidocalcisome maintenance in . J Biol Chem. 24131-40.

  • Rojas V, Galanti N, Bols NC, , Paredes R andMarshall SH. 2010. Induces Apoptosis in Macrophages and Monocyte-Like Cells From Rainbow Trout. J Cell Biochem. 468-476.

  • Jimenez V, Paredes R, Sosa MA and Galanti N. 2008. Natural programmed cell death in T. cruzi epimastigotes maintained in axenic cultures. J Cell Biochem. 105 (3): 688-698.

  • Barrera P, , Tonn C, Giordano O, Galanti N and Sosa MA. 2008. Natural sesquiterpene lactones are active against J. Parasitol. 1143-1149.

  • Paredes R, , Cabrera G, Iragüen D and Galanti N. 2007. Apoptosis as a possible mechanism of infertility of hydatid cysts. J Cell Biochem. 1200-1209.

  • Sanchez AM, , Sartor T, Tonn CE, García EE, Nieto M, Burgos MH, Sosa MA. 2006. A novel icetexane diterpene, 5-epi-icetexone from is active against . Acta Tropica : 118-124.

  • Jimenez-Ortiz V, Brengio SD, Giordano O, Tonn C, Sanchez M, Burgos MH and Sosa MA. 2005. The trypanocidal effect of sesquiterpene lactones helenalin and mexicanin on cultured epimastigotes. J Parasitol. 91(1) 170–174.

  • Jimenez V, Henriquez M, Llanos P and Riquelme G. 2004. Isolation and purification of human placental plasma membranes from normal and preeclamptic pregnancies.  A comparative study. Placenta. 25 (5): 422-437.

  • Alberdi A, and Sosa MA. 2001. The calcium chelator BAPTA affects the binding of assembly protein AP-2 to membranes. Biocell, 167-172.

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